Metal-free reductions of N-heterocycles via Lewis acid catalyzed hydrogenation.
نویسندگان
چکیده
N-Heterocycles form weak adducts with B(C(6)F(5))(3) that exist in equilibrium with the corresponding FLP; nonetheless, these heterocycles are reduced in the presence of a catalytic amount of the borane B(C(6)F(5))(3) and H(2).
منابع مشابه
Metal-Free Hydrogenation Catalyzed by an Air-Stable Borane: Use of Solvent as a Frustrated Lewis Base**
In recent years 'frustrated Lewis pairs' (FLPs) have been shown to be effective metal-free catalysts for the hydrogenation of many unsaturated substrates. Even so, limited functional-group tolerance restricts the range of solvents in which FLP-mediated reactions can be performed, with all FLP-mediated hydrogenations reported to date carried out in non-donor hydrocarbon or chlorinated solvents. ...
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عنوان ژورنال:
- Chemical communications
دوره 46 27 شماره
صفحات -
تاریخ انتشار 2010